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Intracellular recordings to show that APB selectively antagonizes the ON-pathways APB (2-amino-4-phosphobutyric acid, also called L-AP4) is the selective agonist for all Group III mGluRs (mGluR4, 6, 7, and 8)

Concentrations below 100mcg/mL require draw volumes exceeding 0.5mL for typical doses, necessitating larger 3mL syringes

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